This it’s one of the important things to think about when configuring machines with Hyper-V role
Antivirus software it’s one of the “must haves” in almost every system.
Although this is true, for a machine with certain roles (Hyper-V; Exchange; etc.) it’s common and a best practice to configure the antivirus for exclusions of certain folders.
In this case, for Hyper-V, Microsoft’s has a specific Knowledge Base Article.
This may help a lot for increasing performance.
Take a look here:
KB961804 - Microsoft Hyper-V - Antivirus Exclusions
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